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RD TOCRIS一級代理,Z-Guggulsterone供應(yīng)CAS號39025-23-5

  • 更新時間:  2023-07-26
  • 產(chǎn)品型號:  3570
  • 簡單描述
  • RD TOCRIS一級代理,Z-Guggulsterone供應(yīng)CAS號39025-23-5
    我公司代理RD產(chǎn)品和tocris產(chǎn)品
    Z-Guggulsterone
    貨號:3570
    規(guī)格:10mg,50mg
詳細(xì)介紹

RD TOCRIS一級代理,Z-Guggulsterone供應(yīng)CAS號39025-23-5

Catalog Number: 3570

Chemical Name: (Z)-Pregna-4,17(20)-diene-3,16-dione

詳細(xì)產(chǎn)品信息:

Biological Activity
Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. More active isomer of guggulsterone (Cat. No. 2013).

Technical Data

  • M.Wt:

    312.45

  • Formula:

    C21H28O2

  • Solubility:

    Soluble to 20 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming

  • Purity:

    >98%

  • Storage:

    Store at RT

  • CAS No:

    39025-23-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.


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